S Huege); Health-related College of Wisconsin, Milwaukee, WI (Dr P Antuono
S Huege); Healthcare College of Wisconsin, Milwaukee, WI (Dr P Antuono); Oregon Wellness and Science University Aging and Alzheimer Illness Center, Portland, OR (Dr J Quinn); Byrd Alzheimer’s Institute Tampa, FL (Dr A Raj); Collier Neurologic Specialists, Naples, FL (Dr M Baker); University of Kansas Health-related Center Department of Neurology, Kansas City, KS (Dr J Burns); Kylynych Center for Memory Cognition Analysis, Wake Forest University Health Sciences, Winston-Salem, NC (Dr K Sink); California Medical Clinic for Headache, Santa Monica, CA (Dr D Kudrow); Alzheimer’s Analysis Corporation, Manchester, NY (Dr J Shua-Haim); University Hills Estrogen receptor Agonist Source Clinical Investigation, Irvine, CA (Dr MA Knisevich); Behavioral Medical Analysis of Staten Island, NY (Dr J Breving); Collaborative Neuroscience Network, Garden Grove, CA (Dr O Omidvar); Clinical Trials of America Inc., Winston-Salem, NC (Dr B Jones); Radiant Research, Denver, CO (Dr E Duboff); Clinical Study Center of Asheville LLC, Asheville, NC (Dr C Tuten); Suncoast Neuroscience Associates Inc., St. Petersburg, FL (Dr S Cohen); Bradenton Analysis Center, Bradenton, FL (Dr W McElveen); Lynn Health Science Institute, Oklahoma City, OK (Dr S Randhawa); Radiant Study, San Antonio, TX (Dr T Weiss); Fort Wayne Neurological Center, Fort Wayne, IN (Dr F-L Chang); University of Kentucky Health-related Center, Sanders-Brown Center on Aging, Lexington, KY (Dr G Jicha); Agewell Indianapolis, IN (Dr S Rappaport); Premiere Study Institute, West Palm Beach, FL (Dr C Sadowsky and Dr T Villena); Health-related University of South Carolina, Clinical Biotechnology Analysis Institute, Roper St. Francis Healthcare, and Ralph H. Johnson VA Health-related Center, North Charleston, SC (Dr J Mintzer); Radiant Analysis Inc., Chicago, IL (Dr M Kyle); Synergy Clinical Research Center, National City, CA (Dr M Bari); San Francisco Clinical Analysis Center, San Francisco, CA (Dr J Goldstein); Wake Investigation Associates LLC, Raleigh, NC (Dr A Jariwala); Beacon Clinical Research LLC, Brockton, MA (Dr P Sergi); Drexel University College of Medicine Division of Neurology, Philadelphia, PA (Dr C Lippa); Meridien Research, Brooksville, FL (Dr M Farmer); Meridien Analysis, St. Petersburg, FL (Dr G Lefebvre); Northeastern Pennsylvania Memory Alzheimer’s Center, Plains, PAConclusion This S-Connect clinical trial establishes the truth that Souvenaid as an add-on intervention will not slow all round cognitive decline and is safe and effectively tolerated in persons with mild-to-moderate AD employing AD medication. Additional fileAdditional file 1: Table S1. Presenting the nutritional composition of Souvenaid and control solution. Abbreviations AD: Alzheimer’s illness; ADAS-cog: Alzheimer’s Disease Assessment Scale Cognitive Subscale; MMSE: Mini-Mental State Examination; SD: Regular deviation. Competing interests Study design and arranging have been carried out in conjunction with all the sponsor, Nutricia Analysis, on behalf of Nutricia Sophisticated Healthcare Nutrition. The sponsor also supplied the study merchandise and funding for the research, information collection and evaluation. The corresponding author had final duty for the selection to submit for publication. RCS serves around the Board of Directors on the Alzheimer’s Association Greater Illinois Chapter; serves as a member on the Investigator Consultation BRD4 Modulator Compound Network for Merck Research Laboratories; served on a research advisory panel for Accera, Inc., and also a clinical advisory panel for Nutricia, Inc.; receives or lately received investigation.