Biotinylated Fc γ RIV/CD16-2 Protein

Name:
Biotinylated Fc γ RIV/CD16-2 Protein

Synonyms:
Fc gamma RIV, CD16-2, Fcgr4

Species Name:
Mouse

Label Name:
Avi Tag, His Tag

Marker Name:
Biotin

Accession:
A0A0B4J1G0

Gene Id:
Gly21-Gln203, with C-terminal 8*His&Avi tagGLQKAVVNLDPKWVRVLEEDSVTLRCQGTFSPEDNSIKWFHNESLIPHQDANYVIQSARVKDSGMYRCQTALSTISDPVQLEVHMGWLLLQTTKWLFQEGDPIHLRCHSWQNRPVRKVTYLQNGKGKKYFHENSELLIPKATHNDSGSYFCRGLIGHNNKSSASFRISLGDPGSPSMFPPWHQ GGGSGGGSHHHHHHHHGLNDIFEAQKIEWHE

Molecular Weight:
28-35kDa

Purity:
>95% by SDS-PAGE

Physical Appearance Name:
Lyophilized Powder

Endotoxin Name:
<1EU/μg

Reconstitution:
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability Storage:
12 months from date of receipt, -20 to -70 °C as supplied; 6 months, -20 to -70 °C under sterile conditions after reconstitution; 1 week, 2 to 8 °C under sterile conditions after reconstitution; Please avoid repeated freeze-thaw cycles.

Buffer System:
PBS, pH7.4

Quality Statement:
Fc γ RIV (Low affinity immunoglobulin gamma Fc region receptor IV), also known as CD16-2 (Fc γ RIV), belongs to the Fc γ receptor family. There are three types of Fc γ receptors: Fc γ RI (CD64), Fc γ RII (CD32) and Fc γ RIII (CD16). Fc γ RI (CD64) has a high affinity for IgG monomer, while Fc γ RII (CD32) and FC γ RIII (CD16) have a relatively low affinity for IgG. Human CD16 is encoded by two genes, Fc γ RIIIA and Fc γ RIIIB. The gene sequence of CD16-2 is more similar to that of human Fc γ RIIIA protein. The combination of FcγRIV and IgG2a can promote bone cell differentiation. The combination of FcγRIV and IgE can promotes macrophage-mediated phagocytosis, antigen presentation, and proinflammatory cytokine production.

Reference:
1、Hirano M. et al. (2007) IgEb immune complexes activate macrophages through FcγRIV binding. Nature Immunology. 8: 762-771.

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
Corneodesmosin/CDSN Protein
Catalase Protein
Popular categories:
Coxsackievirus and Adenovirus Receptor (CXADR)
CEA Cell Adhesion Molecule 8/NCA-95

Author: Adenosylmethionine- apoptosisinducer

Related Posts